Lab Publications

Journal Articles

All Publications are available upon email request to the Dr Swale at

*Denotes student of the Swale Lab


  1. Edmund J. Norris, Rui Chen*, Zhilin Li*, Werner Geldenhuys, Jeffrey R. Bloomquist,
    Daniel R. Swale. 2022. Neurophysiological and toxicological effects of the sesquiterpenoid, nootkatone, in insects. Pesticide Biochemistry and Physiology.  183: 10508. Click HERE for PDF.
  2. Zhilin Li*, Alexander Soohoo-Hui*, Flinn O’Hara*, Daniel R Swale.   Novel Paradigms for mosquito blood feeding revealed through ATP-sensitive inward rectifier potassium channels.  Communications Biology (IF: 6.3).  5(1): 278. Doi: 0.1038/s42003-022-03222-1. Click HERE for PDF.

  3. Peter M. Piermarini, Jerod S. Denton, Daniel R Swale. 2022. The molecular physiology and toxicology of inward rectifier potassium channels in insects. Annual Review of Entomology (IF: 19.7).  67:125-142.  Click HERE for PDF.


  1. Alexander Soohoo-Hui*, Zhilin Li*, L. Paulina Maldonado-Ruiz, Ganyu Zhang*, Daniel R Swale. 2021. Neurochemical regulation of Aedes aegypti salivary gland function. Journal of Insect Physiology. 129: 104193. Click HERE for PDF.
  2. Sarah E. McComic*, Kumudini Meepagala, Daniel R Swale. 2021. Characterization of toxicological and neurophysiological effects of natural product based chromenes to Fall Armyworm, Spodoptera frugiperda.  Journal of Economic Entomology. 114(6): 2485-2492. Click HERE for PDF.
  3. Sarah E. McComic*, Leslie C. Rault, Troy D. Anderson, Daniel R Swale. Toxicological analysis of stilbenes against the fall armyworm, Spodoptera frugiperda.  Pesticide Biochemistry and Physiology. 171: 104965. Click HERE for PDF.


  1. Leslie C. Rault, Ellis J. Johnson, Scott T. O’Neal, Rui Chen*, Sarah E. McComic*, Daniel R. Swale, Troy D. Anderson. 2019. Age- and sex-related ABC transporter expression in pyrethroid-susceptible and -resistant Aedes aegypti. Scientific Reports. 9:19551. DOI: 10.1038/s41598-019-56134-2. Click HERE for PDF.
  2. Jennifer R. Williams, Daniel R. Swale, Troy D. Anderson.  Comparative effects of technical and formulated chlorantraniliprole on the survivorship and locomotor activity of the honey bee, Apis melliferaPest Management Science.  76(8): 2582-2588 CLICK HERE FOR PDF.
  3. Zhilin Li*, Felicito Guerrero, Adalberto A. Perez de Leon, Lane D Foil#, Daniel R Swale.   Small-molecule inhibitors of inward rectifier potassium (Kir) channels reduce bloodmeal feeding of the horn fly, Haematobia irritans.  Journal of Medical Entomology.  57(4):1131-1140 Click HERE for PDF


  1. Daniel R. Swale and Jeffrey R. Bloomquist. 2019. Is DEET a Dangerous Neurotoxicant? Pest Management Science. Click HERE for PDF
  2. Rui Chen*, Francis J. Prael III, Zhilin Li*, C. David Weaver, Daniel R Swale. 2019. Functional coupling of K+/Cl Cotransporter to GABA-Gated Cl Channels in the central nervous system of Drosophila melanogaster leads to altered drug sensitivities. ACS Chemical Neuroscience. Click HERE for PDF.
  3. Zhilin Li*, Jeffrey A Davis, Daniel R Swale. 2019. Chemical inhibition of Kir channels reduces salivary secretions and phloem feeding of the cotton aphid, Aphis gossypii. Pest Management Science. Click Here for PDF
  4. Zhilin Li*, Kevin R Macaluso, Lane D Foil, Daniel R Swale. 2019. Inward rectifier potassium (Kir) channels mediate salivary gland function and blood feeding in the lone star tick, Amblyomma americanum. PLoS Neglected Tropical Diseases 13(2): e0007153.  Click Here for PDF


  1. Daniel R. Swale, Aaron D. Gross, Quentin R. R. Coquerel, Jeffrey R Bloomquist. 2018. Electrophysiological Recording of the Central Nervous System Activity of Third-Instar Drosophila Melanogaster. Journal of Visualized Experiments (JOVE). (141), e58375, doi:10.3791/58375 Click Here for PDF
  2. Francis J. Prael III, Rui Chen*, Zhilin Li*, Carson W. Reed, Craig W. Lindsey, C. David Weaver, Daniel R Swale. Use of chemical probes to explore the toxicological potential of the K+/Cl Cotransporter (KCC) as a novel insecticide target to control the vector of Dengue and Zika virus, Aedes aegypti. Pesticide Biochemistry and Physiology. Special Issue: ACS Proceedings honoring Dr. Jeffrey Bloomquist. 151:10-17. doi: 10.116/j.pestbp.2018.03.019 Click HERE for PDF
  3. Sheridan J. Carrington, Ciria C. Hernandez, Daniel R. Swale, Jerod S. Denton, Roger D. Cone. 2018. Differential Regulation of Glycosylation and Activity of Potassium Inward Rectifier Channel Kir7.1 by G Protein-coupled Receptors. Journal of Biological Chemistry. 293(46): 17739-17753 Click HERE for PDF
  4. Chris J. Holderman, Daniel R. Swale, Jeffrey R. Bloomquist, Phillip E. Kaufman. 2018. Resistance to permethrin, beta-cyfluthrin, and diazinon in Florida horn fly populations. Insects. 9(63): doi: 10.3390/insects9020063 Click HERE for PDF
  5. Rui Chen* and Daniel R Swale. 2018. Inwardly rectifying potassium (Kir) channels represent a critical ion conductance pathway in the nervous system of insects. Scientific Reports. 8:1617 DOI:10.1038/s41598-018-20005-z Click HERE for PDF 
  6. Daniel R Swale, Jake Z Kraft*, Zhilin Li*, Kristen Healy, Mei Liu, Connie M. David, Zhijun Liu, Lane D Foil. 2018. Development of an autodissemination strategy for the deployment of novel control agents targeting the Common Malaria Mosquito, Anopheles quadrimaculatus Say (Diptera: Culicidae). PLoS: Neglected Tropical Diseases. 12(4): e0006259 Click HERE for PDF
  7. Jackson T. Sparks, Gina Botsko, Daniel R. Swale, Linda M. Boland, Shriraj S. Patel, Joseph C. Dickens. 2018. Membrane proteins mediating reception and transduction in chemosensory neurons in mosquitoes. Frontiers in Physiology. 9:1309. doi: 10.3389/fphys.2018.01309 Click HERE for PDF


  1. Scott T. O’Neal, Daniel R Swale, Troy D. Anderson. 2017. ATP-sensitive inwardly rectifying potassium channel regulation of viral infections in honey bees. Scientific Reports. 7:8668 DOI:10.1038/s41598-017-09448-y Click HERE for PDF
  2. Scott T O’Neal, Daniel R. Swale, Jeffrey R. Bloomquist, Troy D. Anderson. 2017. ATP-sensitive inwardly rectifying potassium channel modulators alter cardiac function in honey bees. Journal of Insect Physiology, 99:95-100. Click HERE for PDF
  3. Daniel R Swale, Zhilin Li, Adalberto A Perez de Leon, Felicito Guerrero, Lane Foil. 2017. Role of inward rectifying potassium channels in salivary gland function and sugar feeding of the fruit fly, Drosophila melanogaster. Pesticide Biochemistry and Physiology. 141: 41-49. DOI:1016/j.pestbp.2016.11.005 Click HERE for PDF


  1. Daniel R. Swale, Darren W. Engers, Sean R. Bollinger, Aaron Gross, Edna Alfaro Inocente, Emily Days, Fariba Kanga, Reed M. Johnson, Liu Yang Jeffrey R. Bloomquist, Corey R. Hopkins, Peter M. Piermarini, Jerod S. Denton. 2016. An insecticide resistance-breaking mosquitocide targeting inward rectifier potassium channels in vectors of Zika virus and malaria. Scientific Reports. 6:36954. DOI: 10.1038/srep36954 Click HERE for PDF
  2. Daniel R. Swale, Haruto Kurato, Sujay Kharade, Johnathan Sheehan, Rene Raphemot, Karl Voigtritter, Eric Figueroa, Jens Meiler, Anna Flobaum, Craig Lindsley, Corey Hopkins, Jerod S. Denton. 2016. ML418: The first selective, sub-micromolar pore blocker of Kir7.1 potassium channels. ACS Chemical Neuroscience. 7(7): 1013-23. doi: 10.1021/acschemneuro.6b00111 Click HERE for PDF


  1. Daniel R. Swale, Jonathan H. Sheehan, Afeef S. Husni, Thuy Nguen, Jens Meiler, Jerod S. Denton. 2015. Computational and functional analysis of the small-molecule binding site in ROMK. Biophysical Journal 108:1094-1103 Click HERE for PDF
  2. Jennifer L Herington, Daniel R. Swale, Naoko Brown, Elaine Shelton, Charles H. Williams, Charles C. Hong, Bibhash C. Paria, Jerod S. Denton, Jeff Reese. 2015 High-Throughput screening of myometrial calcium-mobilization to identify modulators of uterine contractility. PLoS ONE, 10(11): e0143243. Click HERE for PDF
  3. James M. Mutunga, Troy D. Anderson, Derek T. Craft, Aaron D. Gross, Daniel R. Swale,Fan Tong, Dawn M. Wong, Paul R. Carlier, and Jeffrey R. Bloomquist. 2015. Carbamate and Pyrethroid Resistance in the Akron Strain of Anopheles gambiae. Pesticide Biochemistry and Physiology. 121: 116-121 Click HERE for PDF
  4. Sujay V. Kharade, Daniel R. Swale, Jerod S. Denton. 2015. ROMK Pharmacology Comes of Age. Channels. Invited Commentary Based upon Swale et al., Biophysical Journal. 9(3): 119-120. doi: 10.1080/19336950.2015.1046733 Click HERE for PDF