A BRIEF DESCRIPTION OF RECENT SWALE LAB NEWS AND EVENTS
The Swale Lab was awarded an NIH-NIAID R01 award entitled, “Rickettsial influence on host membrane physiology in arthropod vectors.” This project is in collaboration with Drs. Albert Mulenga (Texas A&M) and Kevin Macaluso (University of South Alabama) and aims to define unique aspects of rickettsial influence on tick physiology that enhance pathogenicity of Rickettsia, which will assist in resolving the epidemiology of SFG Rickettsia and reveal intervention points to reduce the health burden of tick borne rickettsial diseases. More information can be found at https://reporter.nih.gov/search/pbza6V-3PEiOdtnIIjpQ3g/project-details/10209566
Zhilin Li (PhD Candidate) was awarded the prestigious Lilian and Alex Feir Graduate Student award in Insect Physiology, Biochemistry, and Molecular Biology from the Entomological Society of America. Congrats, Zhilin.
The Swale Lab was awarded a USDA-NIFA Foundational award entitled, “Novel ways to plug the bug: Unraveling the role of hemipteran Kir channels in feeding and plant pathogen transmission.” This project aims to validate hemipteran Kir channels and the salivary gland as tractable targets for the development of novel antifeedant insecticides to control agricultural insect pests. This award is in collaboration with Drs. Jeff Davis and Zhijun Liu (LSU AgCenter)
The Swale Lab was awarded a USDA-NIFA Foundational award entitled, “Physiological and toxicological relevance of potassium ion channels and reactive oxygen species to honey bee health” The overarching goals of this proposal is to build a functional model characterizing the relationship between KATP channels, ROS, and antiviral immunity in bees and to determine the toxicological relevance of this pathway. This award is in collaboration with Drs. Troy Anderson (UNL) and Mike Finstrom (USDA-ARS)
Congratulations to Rui Chen earning 3rd place in the American Chemical Society, Division of Agrochemicals student competition where she presented her work on the functional role and toxicological relevance of glial Kir channels within insect neural systems.
Congratulations to CJ Fellows earning 1st place in the American Chemical Society, Division of Agrochemicals student competition where he presented his work on the role of K+ ion channels, reactive oxygen species, and antiviral immunity.
Our work on tick salivary glands as a target for control of tick vectored pathogens was highlighted by Forbes. Article can be accessed HERE.
Our tick salivary gland work was summarized and presented in a video released by the American Chemical Society Headline Science channel on YouTube. Click HERE to view the video.
Press release by the Emerging Pathogens Institute at the University of Florida was published to highlight the recent mini-review on the safety of the insect repellent, DEET. You can find the Press release at http://www.epi.ufl.edu/articles/deet—safer-than-you-think.html
ARTICLE DESCRIBING HOW SIEVE TUBE FORMATION AND SAP FEEDING BY THE COTTON APHID IS REGULATED BY KIR CHANNELS IS PUBLISHED IN PEST MANAGEMENT SCIENCE. This work was completed by Zhilin Li. Congrats Zhilin!
ARTICLE DESCRIBING THE FUNDAMENTAL ROLE OF KIR CHANNELS TO THE SALIVARY GLAND FUNCTION AND BLOOD FEEDING ABILITY OF TICKS IS PUBLISHED IN PLOS NEGLECTED TROPICAL DISEASES. This work was completed by Zhilin Li during his Masters thesis. Congrats Zhilin!
ARTICLE DESCRIBING THE METHODOLOGY TO RECORD DESCENDING NERVE ACTIVITY FROM THE FLY CENTRAL NERVOUS SYSTEM IS PUBLISHED IN THE JOURNAL OF VISUALIZED EXPERIMENTS.
ARTICLE DESCRIBING THE CLONING, FUNCTIONAL EXPRESSION, AND TOXICOLOGICAL POTENTIAL OF AEDES AEGYPTI POTASSIUM-CHLORIDE COTRANSPORTER IS PUBLISHED IN PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY. This manuscript was performed in collaboration with Dr. Dave Weaver, Vanderbilt University.
ARTICLE DESCRIBING CHANGES OF GLYCOSYLATION AND FUNCTIONALITY OF KIR7.1 BY G-PROTEIN COUPLED RECEPTORS IS PUBLISHED IN JOURNAL OF BIOLOGICAL CHEMISTRY.PMID: 30257863
REVIEW ARTICLE DESCRIBING THE REPERTOIRE OF CHEMOSENSORY RECEPTORS AND MEMBRANE PROTEINS INVOLVED IN THE TRANSDUCTION OF INSECT GUSTATION AND OLFACTION IS PUBLISHED IN FRONTIERS IN PHYSIOLOGY.PMID: 30294282
Sarah McComic joins the Swale Lab as a Masters Student from Louisiana Tech. Sarah will be working on the development of novel insecticides from natural product origins. Welcome to the team, Sarah.
Zhilin Li, CJ Fellows, Alex SooHoo-Hui, and Rui Chen were all awarded travel grants ($850) from the American Chemical Society to attend the national meeting in Boston, MA
ARTILE DESCRIBING THE HORIZONTAL TRANSFER OF INSECT GROWTH REGULATORS AND NOVEL K+ CHANNEL INSECTICIDES TO CONTROL MOSQUITO VECTORS OF MALARIA IS PUBLISHED IN PLOS: NEGLECTED TROPICAL DISEASES. PMID: 29641515
ARTICLE DESCRIBING THE INFLUENCE OF CHEMICAL INHIBITION OF INWARD RECTIFIER POTASSIUM CHANNELS TO THE NEURAL ACTIVITY OF DROSOPHILA CNS ACTIVITY IS PUBLISHED IN SCIENTIFIC REPORTS. PMID: 29371678